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Nucleic acid medicines - List of Manufacturers, Suppliers, Companies and Products

Nucleic acid medicines Product List

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Features of Aptamers

Features of Aptamers

Fits the shape of proteins! Nucleic acid molecules that can inhibit or regulate.

We would like to introduce the features of the "aptamer" that we handle. Single-stranded nucleic acids form various three-dimensional structures according to their sequences. Utilizing this structural capability, these nucleic acid molecules can bind to target proteins and inhibit or regulate their functions. Please feel free to contact us when you need assistance. 【Features】 ■ Creates a three-dimensional structure that fits the shape of the protein for binding, known as "shape capture." *For more details, please refer to the PDF materials or feel free to contact us.

  • Pharmaceutical Intermediates

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Molecular basis of small nucleic acids that control gene expression and their application in pharmaceuticals.

Molecular basis of small nucleic acids that control gene expression and their application in pharmaceuticals.

Keywords: microRNA, viral defense mechanisms, cell death due to viral infection, siRNA, nucleic acid medicines

mRNA is RNA that contains information for protein synthesis, but there are also many non-coding RNAs in the cell that do not carry messages. We have been elucidating the mechanisms by which immune responses to RNA virus infections are regulated by small non-coding RNAs called microRNAs. Understanding this mechanism may contribute to the development of novel nucleic acid medicines. Additionally, while siRNA also suppresses the expression of mRNA, siRNA has a suppressive effect on a single gene, whereas microRNA acts on entire specific gene groups. Although there are currently no nucleic acid medicines utilizing microRNA, we are hopeful that if the mechanisms of their action in virus-infected cells are clarified, the potential for nucleic acid medicines will expand even further.

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